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MatriStem® (UBM) Research

 

MatriStem Scientific Article List

 

Material Properties


Surface characterization of extracellular matrix scaffolds. Brown BN, Barnes CA, Kasick RT, Michel R, Gilbert TW, Beer-Stolz D, Castner DG, Ratner BD, Badylak SF. Biomaterials. 2009 Oct 12.


Degradation products of extracellular matrix affect cell migration and proliferation. Reing JE, Zhang L, Myers-Irvin J, Cordero KE, Freytes DO, Heber-Katz E, Bedelbaeva K, McIntosh D, Dewilde A, Braunhut SJ, Badylak SF. Tissue Eng Part A. 2009 Mar;15(3):605-14.


Macrophage phenotype and remodeling outcomes in response to biologic scaffolds with and without a cellular component. Brown BN, Valentin JE, Stewart-Akers AM, McCabe GP, Badylak SF. Biomaterials. 2009 Mar;30(8):1482-91.


Extracellular matrix as a biological scaffold material: Structure and function. Badylak SF, Freytes DO, Gilbert TW. Acta Biomater. 2009 Jan; 5(1):1-13.


Oxygen diffusivity of biologic and synthetic scaffold materials for tissue engineering. Valentin JE, Freytes DO, Grasman JM, Pesyna C, Freund J, Gilbert TW, Badylak SF. J Biomed Mater Res A. 2008 Dec 18.


Decellularization and sterilization of porcine urinary bladder matrix for tissue engineering in the lower urinary tract. Rosario DJ, Reilly GC, Ali Salah E, Glover M, Bullock AJ, Macneil S. Regen Med. 2008 Mar;3(2):145-56.


Preparation and rheological characterization of a gel form of the porcine urinary bladder matrix. Freytes DO, Martin J, Velankar SS, Lee AS, Badylak SF. Biomaterials. 2008 Apr;29(11):1630-7. Epub 2008 Jan 16.


Uniaxial and biaxial properties of terminally sterilized porcine urinary bladder matrix scaffolds. Freytes DO, Stoner RM, Badylak SF. J Biomed Mater Res B Appl Biomater. 2008 Feb;84(2):408-14.


Hydrated versus lyophilized forms of porcine extracellular matrix derived from the urinary bladder. Freytes DO, Tullius RS, Valentin JE, Stewart-Akers AM, Badylak SF. J Biomed Mater Res A. 2008 Jan 28.


Immune response to biologic scaffold materials. Badylak SF, Gilbert TW. Semin Immunol. 2007 Dec 11


Maintenance of hepatic sinusoidal endothelial cell phenotype in vitro using organ-specific extracellular matrix scaffolds. Sellaro TL, Ravindra AK, Stolz DB, Badylak SF. Tissue Eng. 2007 Sep;13(9):2301-10.


Identification and characterization of bioactive factors in bladder submucosa matrix. Chun SY, Lim GJ, Kwon TG, Kwak EK, Kim BW, Atala A, Yoo JJ. Biomaterials. 2007 Oct;28(29):4251-6. Epub 2007 Jul 6.


Antibacterial activity within degradation products of biological scaffolds composed of extracellular matrix. Brennan EP, Reing J, Chew D, Myers-Irvin JM, Young EJ, Badylak SF. Tissue Eng. 2006 Oct;12(10):2949-55.


Effect of storage upon material properties of lyophilized porcine extracellular matrix derived from the urinary bladder. Freytes DO, Tullius RS, Badylak SF. J Biomed Mater Res B Appl Biomater. 2006 Aug;78(2):327-33.


Decellularization of tissues and organs. Gilbert TW, Sellaro TL, Badylak SF. Biomaterials. 2006 Jul;27(19):3675-83. Epub 2006 Mar 7. Review.


The basement membrane component of biologic scaffolds derived from extracellular matrix. Brown B, Lindberg K, Reing J, Stolz DB, Badylak SF. Tissue Eng. 2006 Mar;12(3):519-26.


Regenerative medicine and developmental biology: the role of the extracellular matrix. Badylak SF. Anat Rec B New Anat. 2005 Nov;287(1):36-41. Review


Analytically derived material properties of multilaminated extracellular matrix devices using the ball-burst test. Freytes DO, Rundell AE, Vande Geest J, Vorp DA, Webster TJ, Badylak SF. Biomaterials. 2005 Sep;26(27):5518-31.


Production and characterization of ECM powder: implications for tissue engineering applications. Gilbert TW, Stolz DB, Biancaniello F, Simmons-Byrd A, Badylak SF. Biomaterials. 2005 Apr;26(12):1431-5.


Biaxial strength of multilaminated extracellular matrix scaffolds. Freytes DO, Badylak SF, Webster TJ, Geddes LA, Rundell AE. Biomaterials. 2004 May;25(12):2353-61.


Xenogeneic extracellular matrix as a scaffold for tissue reconstruction. Badylak SF. Transplant Immunology. 12 (2004) 367-377.



Myocardial Repair


Increased myocyte content and mechanical function within a tissue-engineered myocardial patch following implantation. Kelly DJ, Rosen AB, Schuldt AJ, Kochupura PV, Doronin SV, Potapova IA, Azeloglu EU, Badylak SF, Brink PR, Cohen IS, Gaudette GR. Tissue Eng Part A. 2009 Aug;15(8):2189-201.


A fusion protein of hepatocyte growth factor enhances reconstruction of myocardium in a cardiac patch derived from porcine urinary bladder matrix. Ota T, Gilbert TW, Schwartzman D, McTiernan CF, Kitajima T, Ito Y, Sawa Y, Badylak SF, Zenati MA. J Thorac Cardiovasc Surg. 2008 Nov;136(5):1309-17. Epub 2008 Sep 14.


The use of extracellular matrix as an inductive scaffold for the partial replacement of functional myocardium. Badylak SF, Kochupura PV, Cohen IS, Doronin SV, Saltman AE, Gilbert TW, Kelly DJ, Ignotz RA, Gaudette GR. Cell Transplant. 2006;15 Suppl 1:S29-40.


Extracellular matrix scaffold for cardiac repair. Robinson KA, Li J, Mathison M, Redkar A, Cui J, Chronos NA, Matheny RG, Badylak SF. Circulation. 2005 Aug 30;112(9 Suppl):I135-43.


Tissue-engineered myocardial patch derived from extracellular matrix provides regional mechanical function. Kochupura PV, Azeloglu EU, Kelly DJ, Doronin SV, Badylak SF, Krukenkamp IB, Cohen IS, Gaudette GR. Circulation. 2005 Aug 30;112(9 Suppl):I144-9.



Esophageal Reconstruction


Evidence of innervation following extracellular matrix scaffold-mediated remodelling of muscular tissues. Agrawal V, Brown BN, Beattie AJ, Gilbert TW, Badylak SF. J Tissue Eng Regen Med. 2009 Aug 21. (also includesbody wall results)


An extracellular matrix scaffold for esophageal stricture prevention after circumferential EMR. Nieponice A, McGrath K, Qureshi I, Beckman EJ, Luketich JD, Gilbert TW, Badylak SF. Gastrointest Endosc. 2009 Feb;69(2):289-96. Epub 2008 Jul 26.


Reinforcement of esophageal anastomoses with an extracellular matrix scaffold in a canine model. Nieponice A, Gilbert TW, Badylak SF. Ann Thorac Surg. 2006 Dec;82(6):2050-8.


Esophageal reconstruction with ECM and muscle tissue in a dog model. Badylak SF, Vorp DA, Spievack AR, Simmons-Byrd A, Hanke J, Freytes DO, Thapa A, Gilbert TW, Nieponice A. J Surg Res. 2005 Sep;128(1):87-97.



Body Wall


Repair of the Thoracic Wall With an Extracellular Matrix Scaffold in a Canine Model. Gilbert TW, Nieponice A, Spievack AR, Holcomb CJ, Gilbert S, Badylak SF. J Surg Res. 2007 Oct 18.



Tunica Repair


Tunica repair with acellular bladder matrix maintains corporal tissue function. Eberli D, Susaeta R, Yoo JJ, Atala A. Int J Impot Res. 2007 Nov-Dec;19(6):602-9. Epub 2007 Aug 2.



Urinary Incontinence


Constructive Remodeling of Biologic Scaffolds is Dependent on Early Exposure to Physiologic Bladder Filling in a Canine Partial Cystectomy Model. Boruch AV, Nieponice A, Qureshi IR, Gilbert TW, Badylak SF. J Surg Res. 2009 Mar 20.


Use of a particulate extracellular matrix bioscaffold for treatment of acquired urinary incontinence in dogs. Jeffrey D. Wood , Abby Simmons-Byrd , Alan R. Spievack , Stephen F. Badylak. Journal of the American Veterinary Medical Association. Apr 2005, Vol. 226, No. 7: 1095-1097.



Orthopedics


Effect of a Xenogeneic Urinary Bladder Injectable Bioscaffold on Lameness in Dogs with Osteoarthritis of the Coxofemoral Joint (Hip): A randomized, Double Blinded Controlled Trial. William Rose, Jeffrey D. Wood , Abby Simmons-Byrd, Alan R. Spievack. The International Journal of Applied Research in Veterinary Medicine. 2009 Volume 7, Number 1 & 2.


Chemoattraction of Progenitor Cells by Remodeling Extracellular matrix Scaffolds. Beattie A, Gilbert TW, Guyot J, Yates A, Badyak SF. Tissue Engineering. In Press.



Tympanic Membrane


Repair of the tympanic membrane with urinary bladder matrix. Parekh A, Mantle B, Banks J, Swarts JD, Badylak SF, Dohar JE, Hebda PA. Laryngoscope. 2009 Apr 8.



Hybrid


Hybrid nanofibrous scaffolds from electrospinning of a synthetic biodegradable elastomer and urinary bladder matrix. Stankus JJ, Freytes DO, Badylak SF, Wagner WR. J Biomater Sci Polym Ed. 2008;19(5):635-52.